Joint Advisory Highlights Threat of Interlock Ransomware
Cybersecurity3 min read

Joint Advisory Highlights Threat of Interlock Ransomware

22 July 202522 July 2025 cisa.gov

The Cybersecurity and Infrastructure Security Agency, alongside key federal partners, issued an advisory focusing on the urgent threat posed by Interlock ransomware. The advisory lays out protection measures for businesses and critical infrastructure.

Key Takeaways

  • 1."This initiative reflects our commitment to protecting the cornerstone of our economy and society — critical infrastructure," said an official from CISA.
  • 2."Preventing initial access is our first line of defense against these attacks," emphasized a representative from the FBI.
  • 3."Ensuring that all systems are current can significantly reduce the attack surface available to cybercriminals," noted a cybersecurity expert involved in the advisory's formulation.

In a recent collaboration, the Cybersecurity and Infrastructure Security Agency (CISA), the Federal Bureau of Investigation (FBI), the Department of Health and Human Services, and the Multi-State Information Sharing and Analysis Center have unveiled a joint advisory aimed at bolstering defenses against the emerging threat of Interlock ransomware. Released on July 22, 2025, this advisory serves as a crucial resource for businesses and critical infrastructure organizations in North America and Europe, providing insights into the tactics, techniques, and procedures (TTPs) associated with recent FBI investigations related to the ransomware.

"This initiative reflects our commitment to protecting the cornerstone of our economy and society — critical infrastructure," said an official from CISA. The advisory not only highlights indicators of compromise inherent to Interlock ransomware but also outlines actionable steps that organizations can deploy to mitigate their risks.

"This initiative reflects our commitment to protecting the cornerstone of our economy and society — critical infrastructure,"

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To combat the threat posed by Interlock ransomware, organizations are urged to take immediate and proactive measures. According to CISA, essential actions include enhancing initial access defenses by adopting domain name system filtering and web access firewalls. Additionally, user training focused on identifying fallacious social engineering attempts is crucial. "Preventing initial access is our first line of defense against these attacks," emphasized a representative from the FBI.

"Preventing initial access is our first line of defense against these attacks,"

Further, organizations are advised to mitigate known vulnerabilities by keeping operating systems, software, and firmware updated and fully patched. "Ensuring that all systems are current can significantly reduce the attack surface available to cybercriminals," noted a cybersecurity expert involved in the advisory's formulation.

"Ensuring that all systems are current can significantly reduce the attack surface available to cybercriminals,"

Person using laptop with holographic cybersecurity shield and digital interface elements
Person using laptop with holographic cybersecurity shield and digital interface elements

Network segmentation is another key strategy highlighted in the advisory, as it serves to restrict lateral movement within organizations once an initial device is infected. "By isolating systems, organizations can contain the spread of ransomware across their networks," a cyber resilience analyst remarked.

"By isolating systems, organizations can contain the spread of ransomware across their networks,"

Moreover, implementing robust identity, credential, and access management policies is essential. The advisory advocates for the use of multifactor authentication across services whenever feasible. This additional layer of security can thwart unauthorized access attempts, making it harder for attackers to infiltrate systems. "Cyber hygiene must become a habitual practice within organizations, not just an afterthought," stated a cybersecurity technician working on enhancing organizational security measures.

"Cyber hygiene must become a habitual practice within organizations, not just an afterthought,"

The #StopRansomware Interlock joint advisory is part of a broader effort to provide guidance to network defenders against various ransomware threats. The initiative seeks to empower organizations with the knowledge and tools necessary to protect their critical assets in an increasingly hostile cyber environment. The resources include not just advisory documents, but also direct links to additional support through stopransomware.gov, which offers further advisories on different ransomware variants.

As cyber threats evolve, ongoing vigilance and adaptive defense strategies become critical in the fight against ransomware. "It’s not just about recovering from attacks; it’s about being able to prevent them in the first place," concluded the CISA official. The joint advisory aims to elevate awareness and inspire action among organizations across sectors.

"It’s not just about recovering from attacks; it’s about being able to prevent them in the first place,"

In conclusion, the Interlock ransomware advisory serves as a crucial reminder for organizations to prioritize their cybersecurity frameworks. With the rise of sophisticated cyber threats, only through collective and proactive efforts can we safeguard our infrastructures effectively. Businesses and institutions are encouraged to stay updated on cybersecurity trends and best practices to remain resilient against inevitable cyber threats that lie ahead.

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